Polycation-DNA complexes for gene delivery: a comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids

Polycation-DNA complexes for gene delivery: a comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids

Source :

• Journal of Controlled Release [ 0168-3659 ] ; 1998.

Descripteurs français

• KwdFr :
  • ADN (), ADN (administration et posologie), Animaux, Cellules COS, Cellules cancéreuses en culture, Humains, Lignée de cellules transformées, Lipides (), Lipides (administration et posologie), Lipides (pharmacologie), Peptides (administration et posologie), Peptides (pharmacologie), Plasmides, Polyamines (), Souris, Thérapie génétique, Transfection.
• MESH :
  • administration et posologie : ADN, Lipides, Peptides.
  • pharmacologie : Lipides, Peptides.
• Pascal (Inist)
  • ADN, Animaux, Cellule tumorale, Cellules COS, Cellules cancéreuses en culture, Complexation, DNA, Expression génique, Homme, Humains, In vitro, Libération, Lignée CACO2, Lignée cellulaire établie, Lignée de cellules transformées, Lipide, Lipides, Lysine polymère, Plasmides, Polyamines, Polycation, Principe actif, Souris, Technologie pharmaceutique, Thérapie génique, Thérapie génétique, Traitement, Transfection, Transfert génétique.
• Wicri :
  • topic : Homme.

English descriptors

• KwdEn :
  • Active ingredient, Animals, COS Cells, Cell Line, Transformed, Complexation, DNA, DNA (administration & dosage), DNA (chemistry), Established cell line, Gene expression, Gene therapy, Genetic Therapy, Genetic transfer, Human, Humans, In vitro, Lipids, Lipids (administration & dosage), Lipids (chemistry), Lipids (pharmacology), Lysine polymer, Mice, Peptides (administration & dosage), Peptides (pharmacology), Pharmaceutical technology, Plasmids, Polyamines (chemistry), Polycation, Release, Transfection, Treatment, Tumor Cells, Cultured, Tumor cell.
• MESH :
  • chemical , administration & dosage : DNA, Lipids, Peptides.
  • chemical , chemistry : DNA, Lipids, Polyamines.
  • chemical , pharmacology : Lipids, Peptides.
  • Animals, COS Cells, Cell Line, Transformed, Genetic Therapy, Humans, Mice, Plasmids, Transfection, Tumor Cells, Cultured.
• Teeft :
  • Absorbance readings, Better cell culture models, Cationic, Cationic lipid, Cationic lipids, Cationic liposomes, Cationic polyamino acids, Cationic polypeptides, Cell culture, Cell culture models, Cell extracts, Cell lines, Charge ratio, Charge ratios, Chloroquine, Colon carcinoma, Complex formation, Complexation, Complexed, Control levels, Data standardised, Direct gene transfer, Dotap, Endosomolytic agent, Enzyme activity, Ethidium, Ethidium exclusion, Fresh chloroquine, Gene, Gene delivery, Gene delivery systems, Gene expression, Gene therapy, Gene transfer, Lipid, Liposome, Little correlation, Malvern instruments, Mammalian cells, Mass ratio, Murine melanoma cells, Nonviral gene therapy, Optimum charge ratio, Particle size, Pharmaceutical scientists, Physical properties, Plasmid, Polyamino, Polyamino acids, Polycationic polymers, Polylysine, Polyornithine complexes, Pouton, Power spectra, Protein content, Prsvlacz, Prsvlacz complexed, Relative activities, Reporter gene, Room temperature, Standard curve, Sterile water, Total charge ratio, Transfect cells, Transfected, Transfection, Transfection medium, Zeta, Zeta potentials.

Abstract

• https://api.istex.fr/ark:/67375/6H6-38LZC4R8-6/fulltext.pdf

Affiliations:

• Royaume-Uni

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